SUPRELORIN® F (deslorelin acetate) Implant

SUPRELORIN® F Implant is a once-yearly, subcutaneous implant that assists in the management of adrenal disease in ferrets.

  • Ferret

Virbac is proud to offer SUPRELORIN® F (deslorelin acetate) Implant, available only through licensed veterinarians.

According to the American Veterinary Medical Association (AVMA), there may now be more than one million pet ferrets across the United States. Ferrets also at risk of adrenocortical disease (ACD) – a disease that, if left untreated, can greatly affect a ferret’s quality of life and can even be fatal.

  • Hair loss – alopecia is a common sign of ACD
  • Vulvar swelling – in about 50 percent of female ferrets with ACD, chronically high estrogen levels cause a swelling of the vulva
  • Unusual sexual behavior and aggressiveness – a sterilized male ferret that suddenly begins behaving as if he had not been neutered could have ACD
  • Difficulty urinating – high androgen levels can enlarge the prostate gland in male ferrets, causing urinary straining
  • Lack of energy – a lethargic ferret – one that exhibits drowsiness, inactivity, listlessness and indifference – may have ACD
  • Muscle atrophy – muscle wasting or loss can be seen in ferrets with ACD
  • Skin disorders and itching – along with hair loss, ACD can cause dry, flaky skin

About SUPRELORIN F Implant

Because of the nature of ACD in ferrets, there is no true cure for the condition. Now that the SUPRELORIN F Implant is available in the United States, ferret owners have a simple, convenient medical alternative for controlling the clinical signs of the disease. Studies have shown that the most common signs of ACD are all reduced quickly after implantation of the SUPRELORIN F Implant, and most resolve for up to one year.

Safety & Efficacy of SUPRELORIN F Implant

SUPRELORIN F Implant has been shown to be safe for use in ferrets. 1-3 In the U.S., SUPRELORIN F Implant is available as an implant containing 4.7 mg of deslorelin acetate. Published studies have found the SUPRELORIN F Implant safe for use in ferrets with appropriate clinical monitoring. It is possible that treated ferrets will show some soreness and swelling at the implantation site, which should resolve over one to two weeks.3 Other reported side effects include weight gain, lethargy and failure to respond to therapy. Blood tests were shown to be within the normal range after treatment.2 SUPRELORIN F Implant has also been demonstrated as effective.1-3 Results from published studies have shown that the most common signs of ACD are all reduced quickly after implantation with SUPRELORIN F Implant, and resolve for up to one year.1-4 Studies demonstrated that the 4.7 mg deslorelin acetate implant was effective. 1-4


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Download the Product Insert

SUPRELORIN® F (deslorelin acetate) Implant - For use in ferrets only. Do not use in animals intended for breeding. The safe use of this product has not been evaluated in pregnant or lactating ferrets. Do not use this product in ferrets with known hypersensitivity to deslorelin acetate or other synthetic hormones. DO NOT HANDLE THIS PRODUCT IF YOU ARE PREGNANT OR NURSING OR SUSPECT YOU MAY BE PREGNANT. Accidental administration may lead to a disruption of the menstrual cycle. For complete product information refer to the product insert. To obtain a package insert, contact Veterinary Technical Product Support at 1-800-338-3659.

In clinic use only.


  1. Literature on file, Virbac Animal Health. 
  2. Wagner RA, Piché CA, Jöchle W, Oliver JW. Clinical and endocrine responses to treatment with deslorelin acetate implants in ferrets with adrenocortical disease. Am J Vet Res. 2005;66(5):910–914. 
  3. Shoemaker NJ. Everything you wanted to know about adrenal disease in ferrets. In: Proceeding of the North American Veterinary Conference (NAVC); January 19–23, 2008; Orlando, FL. Available at: http://www.ivis.org/docarchive/proceedings/navc/2008/sae/675.pdf. Accessed October 17, 2011.
  4. Wagner RA, Finkler MR, Fecteau KA, Trigg TE. The treatment of adrenocortical disease in ferrets with 4.7 mg deslorelin acetate implants. J Exotic Pet Med. 2009;18(2):146–152.

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Product Options

2 ct 4.7 mg Implant

Implants in box

5 ct 4.7 mg Implant

Implant in box