kooijker dog with sunset


CLOMICALM® (clomipramine hydrochloride) tablets

An effective treatment for canine separation anxiety as part of a behavioral management program.

  • Dog

Download the Prescribing Information

CLOMICALM tablets are to be used as part of a comprehensive behavioral management program to treat separation anxiety in dogs greater than 6 months of age. Inappropriate barking or destructive behavior, as well as inappropriate elimination (urination or defecation) may be alleviated by the use of CLOMICALM tablets in conjunction with behavior modification.

Safe and Effective

  • CLOMICALM® Tablets, along with behavior modification, may help alleviate inappropriate barking and elimination (urination or defecation), as well as destructive behavior
  • While CLOMICALM® Tablets are not a sedative drug, it may cause lethargy in some dogs.


Trusted for more than 20 years.

Separation anxiety is not an expression of anger. It is a distress response characterized by:

Clomicalm-chart.jpg (Clomicalm Redesign v7-fullRes)


CLOMICALM® (clomipramine hydrochloride) tablets:
For use in dogs only. Keep out of reach of children. In children, accidental ingestion should be regarded as serious. Do not administer to dogs with hypersensitivity to clomipramine or other tricyclic antidepressants. CLOMICALM tablets should not be used in: 1) male breeding dogs; 2) combination or within 14 days before or after treatment with a monoamine oxidase inhibitor; 3) dogs with a history of seizures or concomitantly with drugs which lower the seizure threshold. CLOMICALM tablets are not recommended for other behavior problems such as aggression. Effectiveness and clinical safety for long-term use (i.e., for >12 weeks) has not been evaluated. To reduce the incidence of vomiting that may be experienced by some dogs, CLOMICALM tablets may be given with a small amount of food. For full prescribing information, contact Virbac at 1-800-338-3659 or download the product insert.