kooijker dog with sunset

Skin Health

CYCLAVANCE™ (cyclosporine oral solution) USP MODIFIED

Relieve your dog’s atopic dermatitis with a liquid treatment that’s easy to give.

  • Dog
  • Oral solution
    Oral solution

Happiness is getting your dog’s


Download the Prescribing Information

The scratching and skin lesions associated with atopic dermatitis can be painful for your dog and upsetting to you. Now, there’s a proven treatment that’s easy to administer, leaving you both a lot happier!

What is atopic dermatitis?

Atopic dermatitis is a common skin disease in dogs caused by allergens, such as house dust mites or pollens, which trigger an exaggerated immune response. The disease is chronic or long-lasting and must be managed over the course of your dog’s life.1


What are the signs of atopic dermatitis?


What is CYCLAVANCE™ (cyclosporine oral solution) USP MODIFIED?

CYCLAVANCE oral solution is for use only in dogs to control atopic dermatitis. It is proven to be effective and safe in reducing the itch, inflammation and skin lesions associated with atopic dermatitis—helping to return your dog to a happy state of being.Ask your veterinarian if CYCLAVANCE oral solution is a good option for your dog.



When can I expect to see results?

CYCLAVANCE oral solution should be given daily until improvement is seen. This will generally be the case within 30 days or less.3

  • You may notice a gradual improvement in your dog’s condition before then
  • Digestive tract problems and increased gum tissue growth may occur at the initial recommended dose


Happiness is a treatment that’s


How do I give CYCLAVANCE oral solution to my dog?

At least 1 hour before and 2 hours after feeding, administer CYCLAVANCE oral solution directly into your dog’s mouth following the step-by-step instructions shown here. Give once daily until you and your veterinarian are satisfied with the improvement. Be sure to talk to your veterinarian before changing your dog’s treatment routine.1


What else should I know about CYCLAVANCE oral solution?

CYCLAVANCE oral solution may cause elevated blood sugar levels in diabetic dogs. Use with caution in dogs with kidney disease, or in combination with azole antifungals, like ketoconazole, which suppress enzymes that break down these drugs. Killed and non-modified live vaccines should be used in dogs receiving CYCLAVANCE oral solution.


How do I administer CYCLAVANCE oral solution?




Happiness is


feel good in its skin


Relieve the itch and reduce skin lesions caused by atopic dermatitis 


Consult with your veterinarian for questions about your dog's atopic dermatitis and ask if your dog could benefit from CYCLAVANCE™ (cyclosporine oral solution) USP MODIFIED treatment.



For Veterinary Professionals:

We have a separate website specifically tailored to veterinary professionals with more in depth information on all of our products. Click here to view this product's page on our vet website!


Important Safety Information
CYCLAVANCE™ (cyclosporine oral solution) USP Modified: For use in dogs only.
Wear gloves during and wash hands after administration. Gastrointestinal problems and gingival hyperplasia may occur at the initial recommended dose of CYCLAVANCE Oral Solution for Dogs. CYCLAVANCE Oral Solution for Dogs should be used with caution: 1) in cases with diabetes mellitus as it may cause elevated levels of serum glucose; 2) in dogs with renal insufficiency since the effect of cyclosporine use on dogs with compromised renal function has not been studied; 3) in simultaneous administration with drugs that suppress the P-450 enzyme system, such as azoles (e.g. ketoconazole), that may lead to increased plasma levels of cyclosporine. Killed vaccines are recommended for dogs receiving CYCLAVANCE Oral Solution for Dogs because the impact of cyclosporine on the immune response to modified live vaccines has not been evaluated. For full prescribing information, contact Virbac at 1-800-338-3659 or view the Product Insert.



1. CYCLAVANCE™ (cyclosporine oral solution) USP MODIFIED [product label]. Fort Worth, TX: Virbac AH, Inc.; 2020.
2. Navarro C, Crastes N, Benizeau E, McGahie D. Voluntary acceptance and consumption of two oral ciclosporin formulations in dogs: two randomised, controlled studies. Ir Vet J. 2015;68:3.
3. Steffan J, Parks C, Seewald W. North American Veterinary Dermatology Cyclosporine Study Group. Clinical trial evaluating the efficacy and safety of cyclosporine in dogs with atopic dermatitis. J Am Vet Med Assoc. 2005;226:1855–1863.

Other related products

ALLERMYL® (Piroctone Olamine) Medicated Shampoo

Read more

EPI-SOOTHE® Cream Rinse

Read more


Read more

KERATOLUX® (Piroctone Olamine) Medicated Shampoo

Read more

GENESIS® Topical Spray (0.015% triamcinolone acetonide)

Read more

KETOCHLOR® (Chlorhexidine Gluconate, Ketoconazole) Medicated Shampoo

Read more